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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '653074fc2062ca5cc8eeac3f1b8cf1ea52779ad1b2b1efa9b65ab244b2524561' 
  AND token = '2P/NYdrtbWUexzwVWwlrJv5MRReQcYdnX7FvS+JqIHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}