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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee53e772289195f9606722a476952c6526add2c84086b5f6d6e24896124b1e61' 
  AND token = 'RtVxxeZz50DSnq2q0Tx61+tO47bthRJjdSua9HNJ70E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}