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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e8625b5df6ae0893ee0133265458aa054f37d5686c1a3b54a410794b1b69780' 
  AND token = 'IfIkvg6tchB4IdXpRtAozmBqAOAQVF3Vu2DMjjIOFPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}