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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24d82358135252e75cc19a045c06e50d234ad1af5c8a6b964e1d991d41ad3d89' 
  AND token = 'ZQuyeuG9UVdtTvp1eLagdKpBV6n5iVh3z2EuioIqV/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}