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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78f6a60e98d83de0515094717a38d2a2a39580fce33c0370af806fb8121dd7d2' 
  AND token = '0+vQrZ+V7Wcpn30FiFoz4CBHb7B2RGyHA/kW18Tu4pE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}