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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5011cd8aff7343a6afbe978aedea0fc1a137ee3f1a33f67d25ae59e89109e8d2' 
  AND token = 'fJdUu1EOjuMLVCNWeJT9fxhC3GV5IEJOA+u19mUGxjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}