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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1975c1fe67636fb8789a67b9c4e1e2233b2293f9033099546a5bdd780aa31775' 
  AND token = '4rnpeenaJ7308uYL7dB/XNtJBPdRDArEIv1/sYoA3tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}