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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb788383645704b39d15c325a3cc900c65ba7abe6b92154583602ede002127a6' 
  AND token = 'D/vg12RIfP1BoJ5rL2wZeaB4WcEFejZ2L0GCENfrgKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}