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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6ac01892b9c46a66b300d96863b52978da4f5ae832d3777dfea03ffe6ffa482' 
  AND token = 'pOwW8An+dDPsfmuvs9KI8G/sh0vEMfnWpLaT/m+jDlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}