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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e0773417862f82022bb8d7b63321b7358d7c118203fc7df41215f741cf30fa9' 
  AND token = 'OP3n/0C4q+asHq1528cUaPGyZEvBD5z0ZWW/1wlYITk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}