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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac25a21b4c2f45387625955f796e084adca6b889f8247d1bffb8d56d8f983834' 
  AND token = 'jVuhwa+RzrnE/+42UIBXbT05N8IHubQn+wcyKBh4t98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00071

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}