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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2e10300e088996cf4a796176433bdfee42299aa66fdb8dcc1d730e6991854c6' 
  AND token = 'mImAEm5YihuYUwGzLR0y5JqbsAr8YF2W8l7aX06HYUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}