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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38621d64ee94b5e738c86c431c34003eb3e63a42d1945bec40d5a3e958674518' 
  AND token = 'nFQjnGbXzsU/Usw/wcUH+pSCrvTODWMdFFUxzHlKEEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}