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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c55d4ebb2e2175714c97b4bdc21d432e73bc80f43f7551ce0144df34eb6054bf' 
  AND token = '4+H/AdV1NNO0r3A6UTmgxnL9aD1eosQ3BgRPwDD6VrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}