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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d8d4eb0e40e70a08c6d61097c7e16acea7abb483ae333de671b6c6903b2912e' 
  AND token = 'mZGIwoEOPJoe088WWq1v0C3y2QJH2UDLwvSZk+Z0R8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}