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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b60b1e1f413b33c0fcf41159501d944b4da7d1d06821d18aadea0df9037bec42' 
  AND token = 'fp5PbTqC/9HFNpgoDhWUXByiZ5Wbal52TBuxRWk+ngc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}