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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1fe8be4723c6e9e53ea90c060b60775825a240cfcaead938aad7ff54b638ce5' 
  AND token = '0q/N7z45lyJm23y74bmjje1/UU/GM15CIlxrGmejFkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}