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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4deca2eff2227177280a74f65922cb5d5302d0831b1c20f180c89b444584374c' 
  AND token = 'Tp3ItrVOU6prLKJHwWaRJ2xt2WymJplELNdX9tgq4jo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}