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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59f742958998fb117bf3cb3c3148dcef2b2c146d543261e46f9e6b2ba93c79a0' 
  AND token = 'gTn8F++Zzx+u4/ak5k9yw2Db6JB0TFgsiWQx4ZfSU8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}