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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec773be3a71aa52066536a5cd7eec650e2b1daa264b80a23d0017c66b87386f6' 
  AND token = 'jydo8T8irkK1xxnrPVZxjnoO+oTRrMuhF8/fI1E+5tw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}