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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c1ddd484203d2493880b7a2b665c2b09fb6d5802f7ca2a7a0799074d523a85e' 
  AND token = 'icbJ6w87KTPS/kWddgDHM+Sx7uknQfCfqzhtv32jEM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}