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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aeb5496b4cdf7cbf1b1a6ea2d298559d19336976e15cb1ff460069c9b47da6fc' 
  AND token = 'GI+GlQLb5CXxrSS7sa1x+Y6/Rnj4fHbfT6E1VqtPzbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}