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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f657b9e5e3447e11fe74f5fafb46dc27969083d510b7d21e65e8ea3995b0ef8' 
  AND token = 'K8xJ3F7O34yM1Wr+dxpw6qB9gobvsALL6lXLa9fniKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}