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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd35e0de1be384b40e0cc8c6f6175b6aacee1480b3b81860163aaaa4e11d5cf2a' 
  AND token = 'S4eIMLCgHeTv5UA5iZ5C4nmcuOhWC4FZd29LDb57/zo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}