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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e286fd293baf64e72f49df2563cf163f02f4b5383c2d87e9956d2d74cc0abba2' 
  AND token = 't3YlCkSBb0rh3UjmcIE1gyfSPDUaHVtHYabJEQpCTp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}