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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40eddb1858a3f92967196a8eebba9d60afe7a5e8239f5b4f0a2aa0628f58667a' 
  AND token = '2tuHo05wWKl4Ztek57MYr35652f6A81I6cIYBrsKHgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}