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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '534b50cc0bb441a9595653377ec47d9d69ed0edcfd81c7d0c1138c0b7228ad96' 
  AND token = 'sUXew1c5ysaOJqHe5VbTKIXVHxcPg7KuuCztMxmHJ2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}