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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '964087f26a017b7a9618bd3e2771090cc262c18b73e8acbc05b93695a0b7c520' 
  AND token = 'ezltCqYk447uN09QzoZz69WwjdwxMa4Nxm1KRa5qRBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}