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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0fd8b09180b4d34bda904abb19dad36fb2e859ca0d35ff9b6cade7652a74ed4' 
  AND token = 'tfLSlsxSdEezDE8I24SOneFBOfwxHkx4CRuJ4cQwbKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}