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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3678d486765932757080b39570569fd336eba290222025e03fb1b0d8293909d' 
  AND token = 'lPeEQSKYrGs0JeU9a6ET3ThW5heYmpyAEMRqaaAC2G0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}