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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f10e41a9e9c5a5b31c6cb8198c68bf1419a1ee3937100215082528eee523950' 
  AND token = '26aGkG1PaMbyf8wib4ItTzfa3vhcoiCNvOyzqNNxS14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}