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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72865d14b6c0acfbf8a4f466c4e574dda89b7da6c2ea55836cc8365de24c265f' 
  AND token = 'BLiVsf1Tx6zKaS2gLxL4Gpk3F5mxGGdISYbKACu/r+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}