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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b8d310448fa5ace30688b24e2991d4783c78ca8ad024c95f7d72483df92662c' 
  AND token = 'lxwxxT0IAAWyZVWqlEpoMeN6arnyKQMPAkToVTmC1nI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}