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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9e1cd50a74ab7ff1e72adb8714d0635d545105681ac79f961eae1ade2882f30' 
  AND token = 'IG1OMF9eMCXLX5psh2WGEnz89EIAHEuXCrYTID7siPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}