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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca07e8c463be6b073c94d678efe006c5f887bc449a6c2c198c13b19ac054f866' 
  AND token = 'HFSDAYBDOr/5h1oYKiUR19BLkKO0E4TvaCcasHy8sSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}