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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80586dd513f832212a7b3cb015a1dee27169b86a54304ab775673f70a896a2cb' 
  AND token = 'wF9a/YNSbd0xOmHnTgjvcPHOYHY84uAVOhLHbX2+6x0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}