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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a18d01fbd2d8a31cd1ce7aefb706b4e71fc9893912a30094c5f173c7b4ef642' 
  AND token = '9WleNx+ELT/V1K+HzdDZ0P+yWMjdSKzCfif52oOgu/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}