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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c42001d096448aa375e864b78392cb2599672bb17ad92f2314e7ad3573e065d6' 
  AND token = 'UTiT8N+/VMEdlXbKfSS+U/3vI9c+/ZfqkPac+SG8ruw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}