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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af51b1130ae431a6055a207aeca9c3f7340e730bc03182ce856523c1e4dff542' 
  AND token = '7+lFPSCqvGI+a004GfFUvcTF4GDwvweeHhvL+AQ9Ds8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}