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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '469a429bcdac9ab2fd7cea387c66b2e905c2b6f8bd84e2b842f0054028f261fe' 
  AND token = 'UTBrBkfiUGSNaQDk5H5OVcg5OoFfxu0CurbZlNGA13g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}