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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc85976697bf49bf6bffd516354c89b17c90f0ce55730e4d780c70fbeba3e4fc' 
  AND token = 'ZkiURNYuge6JSt6PgPQ9lh0Ds7Cli4k8lshWO5bAQgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}