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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '522defae7213b384b1aceb7b8f0a10b3f1e2a838c45d7213bd96c3c4ff997979' 
  AND token = '80S+ByKESHijkCxNKzbaS2N2But3+T3BeTb5cB6wR3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}