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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75b0e8089dd7329b31f28abc027280bd4d5855a290a4d655a76c9de776cb9aba' 
  AND token = 'W0WS3YNFSLYB1eSVm+NfDhBERk2CnheDIjBP2JF7/JA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}