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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c2f6e0ee4772cabd206de4244a429677feaf4797ecbaf020c39c360a0e90362' 
  AND token = 'SkwH6Y4+gptW1Bxqvd/djcdvM2aQfute9IudVwb6aLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}