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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4fe7e40a6a724f53f6803fd555690190787ae5df817248db2c90a2a1eabd2ca' 
  AND token = 'MdKRQj3mAOC2b2k7D/5VjZjlpXII/WEU1a/7RZ3r+8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}