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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ed93281d09e7e047b14c6d05b9bb30ed1b74b052d3dc6f37135786a4fd810c1' 
  AND token = 'sUIZq6J2wsECxEsQ9GLvF9R9EQNnAMR0BvOh/DjewZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}