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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00ad13c030f9764e166d6f7ca872c74801e266fadf7dac8dec8c611149d6b64a' 
  AND token = '+6yYmyBeinoxefVi3MBjXEbdAc658PaqfH8Dd/9SI3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}