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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f854ee0b9ea7355d5f3c55436fcb3975287a720c401db28908d7888fe8d1003d' 
  AND token = 'ssPqM0CMx+lCbLUE9GT61UHbTvHw0O1NIsjBAh4usCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}