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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dca0f14c0dcaa00a4714b7a01e9b43807d4c93f893c7a068fea8782a3e796b2' 
  AND token = 'ND+G3lco7gUPu5Gsci50r+1EPDom9Vf1YKZ4FpvkcUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}