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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4dd3e1dfe51d4d0b2507d622fbf2148033527737ba7851ea39cd6ae32c6ef63' 
  AND token = 'GdMwpS5Wm1IvQwO02y8ea8bGz4lSB0gK1H4ClcJTKnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}